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Ondansetron is the generic name of the drug which was first produced and marketed under the brand name Zofran by GlaxoSmithKline.

Ondansetron 4mg

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What are Ondansetron uses?

Ondansetron is mainly used alone or with other medications in order to prevent nausea and vomiting caused by cancer drug treatment such as radiation therapy as well as chemotherapy. This medicine is also effective in preventing nausea as well as vomiting after having surgery.  Ondansetron tablet functions in your body by blocking one of the body’s natural substances known as serotonin which causes vomiting.  

This medicine is also used for treating morning sickness and stomach flu.   

Oral Ondansetron therapy is very effective in reducing the frequency of vomiting as well as IV fluid administration in infants as well as children who are six months to 12 years old.  

Ondansetron generic drug is available in the brand name of Zofran ODT. Therefore, you can purchase this medicine from our pharmacy at a reasonable cost.  

Ondansetron orally disintegrating tablets are mainly given for avoiding nausea as well as vomiting which is caused due to certain medical treatments like chemotherapy.

What is the dosage of Ondansetron?

It is very important for you to take this medicine as prescribed by your doctor if you want to get the most benefit from it. Strictly follow all the directions that are mentioned on your prescription label. Do not take Ondansetron medication in a smaller or larger amount as well as for a longer time than recommended by your doctor.  

This medicine is dissolved on the top of the tongue. Ondansetron tablet is not meant to be chewed or swallowed like any other tablet forms. Before using this medication make sure that you dry your hands properly. If you are using blister pack, then first peel back the foil on the blister pack in order to remove a tablet. Remember that you should not push the tablet through the foil. As soon as you remove the tablet, place it on your tongue. Allow the Ondansetron orally tablet to dissolve completely and once it is dissolved swallow it with your saliva.  

You do not require to take this medicine along with water because doing so can increase your chance of getting a headache.  

In order to prevent nausea from chemotherapy, you need to take this medicine usually within 30 minutes before the treatment begins. If you want to prevent nausea from radiation treatment then take this medicine 1 to 2 hours before the start of your treatment. In order to avoid nausea after surgery take Ondansetron medication one hour before your surgery starts. You can take this medicine with or without the food as directed by your doctor.  

Therefore, there are chances that your doctor might tell you not to eat food before your chemotherapy, surgery or radiation therapy.

You strictly need to take the doses as directed by your doctor. There are chances that your doctor tells you to take this medicine up to 3 times a day for one to two days after your chemotherapy or radiation therapy is finished. If you want to take the most benefit from this medicine then it is very important to take it on a regular basis and also on a prescribed schedule. Take this medicine at the same time each day so that you remember to take it. 

This medicine is available in different strengths like Ondansetron 4mg and 8mg. So the dosage of this medicine is completely based on your medical condition as well as response to the therapy. The dosage for children is based on age as well as weight.  

People who are suffering from serious liver problems for them the usual maximum dose is 8 grams in 24 hours. Make sure that you take this medicine is exactly in the same manner as prescribed by your doctor. Always ask your doctor or pharmacist if you have doubt about this medicine.  

If your condition does not improve or gets worse then make sure then contact your doctor immediately.  

Always measure the liquid medicine with the dosing syringe which is provided with the medicine or with the dose-measuring spoon. If you do not have the dose-measuring device then ask your doctor for one.  

Always store the medicine at the room temperature right from direct light and moisture. Make sure that you store the liquid medicine in an upright position.   

What happens if you miss a dose? 

The moment you remember, take the missed dose. But if it’s time for your next dose then skip the missed dose because two doses should not be taken at the same time. Do not take extra medicines just to cover the missed dose.  

What do you need to avoid while taking this medicine?   

Ondansetron tablet is known to impair your thinking as well as reactions. So avoid driving as well as using machinery that requires attention.  

Can you take Ondansetron during pregnancy? 

Ondansetron medication is not expected to harm an unborn baby. So if you are pregnant then immediately inform your doctor.  

Can a breastfeeding mother take Ondansetron? 

It is still unknown whether Ondansetron ODT passes into the breast milk or not or whether it harms a nursing baby. So it is better to consult your doctor before breastfeeding.  

This medicine should not be given to children who are younger than 4 years old.  

Ondansetron 4 mg disintegrating tablet might contain phenylalanine. So inform your doctor if you have phenylketonuria.  

Precautions to be taken while using Ondansetron 

Before taking Ondansetron 4mg and Ondansetron 8mg make sure that you inform your doctor or pharmacist if you are allergic to it or to other anti-nausea serotonin blockers such as granisetron. Also, inform your doctor well in advance if you have any other allergies. Ondansetron ODT 4mg and 8 mg are known to contain certain inactive ingredients that might cause you allergic reactions or other problems. So talk to your doctor about this beforehand only.  

Before you start your Ondansetron medication, always tell your doctor in advance about your complete medical history especially if you have ever suffered from irregular heartbeat, stomach/intestinal problems (like abdominal surgery & swelling) as well as liver disease.  

This medicine can cause a condition which can affect your heart rhythm also known as QT prolongation. QT prolongation can hardly cause severe fast or irregular heartbeat as well as other symptoms such as fainting & serious dizziness that requires immediate medical attention.   

Remember that you can increase the risk of QT prolongation if you suffer from certain medical conditions or are taking other drugs that can cause QT prolongation. Before you start taking this medicine tell your doctor or pharmacist about all the drugs that you are taking and also if you are suffering from any medical conditions such as heart problems like (heart failure, slow heartbeat and QT prolongation in the EKG), family history of certain heart problems such as sudden cardiac death and QT prolongation in the EKG.  

Low levels of potassium or magnesium in the blood can increase your risk of QT prolongation. This risk can be increased if you are taking certain drugs like diuretics or water pills or if you are suffering from serious conditions such as diarrhoea, sweating and vomiting. So it is always better to consult your doctor properly before you start taking Ondansetron.    

Ondansetron medication can make you feel dizzy or drowsy. Intake of alcohol or marijuana can make you feel more dizzy or drowsy. Due to this reason, it is recommended not to drive, use machinery or do anything which demands alertness until you are sure that you can do it safely. Avoid all kinds of alcoholic beverages. It is better to tell your doctor well in advance if you use marijuana.

In order to minimize dizziness as well as lightheadedness make sure that you get up slowly when rising from a sitting or lying position. Ondansetron might contain aspartame. If you are suffering from phenylketonuria or any other condition which requires you to restrict your intake of aspartame. Consult your doctor about the safe use of this medicine beforehand.    

There are chances that older adults may be more sensitive to the side effects of this medicine mainly QT prolongation.   

Always keep this medicine away from children. You should never share your medicine with others even if they have the same symptoms just like yours. Do not use Ondansetron tablet for a longer time than prescribed by your doctor.  

What are the Ondansetron side effects? 

Remember that your doctor has prescribed you this medicine only because he or she thinks that the benefits of this medicine are more as compared to its side effects. Many people using Ondansetron tablets have not come across any serious side effects.  

Some of the common side effects of this Ondansetron tablets are:

  • Tired feeling 
  • Headache, drowsiness
  • Constipation
  • Diarrhoea

You need to contact your doctor immediately if you come across any signs of an allergic reaction while using Ondansetron. Get the emergency help if you suffer from:

  • Rash
  • Swelling of your face, throat, lips or tongue
  • Hives
  • Fever & chills

Contact your doctor immediately if you suffer from: 

  • Bloating, serious constipation
  • Stomach pain
  • Fast or pounding heartbeats, fainting, headache with chest pain and serious dizziness
  • Blurred vision or temporary vision loss
  • Jaundice
  • Signs of high levels of serotonin in the body like hallucinations, fainting, agitation, fast heart rate, vomiting, fever, overactive reflexes, loss of coordination as well as diarrhoea

Therefore this is not the complete list of side effects. In case you experience anything apart from this list then contact your doctor immediately.

Ondansetron Interactions 

Remember that this medicine can cause severe heart problems if you are taking certain medicines at the time of Ondansetron medication. Certain medicine includes heart rhythm medicine, antibiotics, antipsychotic medicines, medicines to treat cancer, HIV or AIDS as well as antidepressants. It is always recommended to tell your doctor about all the medicines that you are using right from prescriptions drugs, non-prescription drugs to herbal products. Do not start, stop or change the dosage of any medicine when you are going through the treatment with Ondansetron.  

It has been seen that when you take this medicine along with certain other medicines that Ondansetron tablets have caused high levels of serotonin to build up in your body, a condition known as serotonin syndrome which can be deadly. So it is better to inform your doctor well in advance if you are also using:

  • Medicine to cure depression
  • Medicine to avoid vomiting as well as nausea
  • Medicine to treat a psychiatric disorder
  • A narcotic medication

There are also many drugs that interact with Ondansetron medication such as vitamins & herbal products as well as over-the-counter medicines. So it is always better to provide a list of all the products that you are using to your doctor or healthcare provider.  

You should never take Ondansetron drug if you are already taking apomorphine because it can cause serious interaction.  

There are total 295 drugs that are known to interact with this medicine.

110 major drug interactions

180 moderate drug interactions

5 minor drug interactions 

Some of the names of drugs that interact with Ondansetron tablets include Advil, Doxycycline, Hydrocodone, Lorazepam, Omeprazole, etc.  

How do Ondansetron works? 

Ondansetron medication functions in your body by blocking the actions of chemicals in your body that is capable of triggering nausea as well as vomiting. 

Ondansetron Warnings 

This medicine should not be used if you are also using apomorphine. Before you start your medication make sure that you inform your doctor if you are suffering from liver disease or a personal or family history of long QT syndrome. 

We only ship medications which are approved by FDA, Also please consult your doctor to make a full decision on what medication to take.

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