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Home / Diabetes / Glipizide


Glipizide is an anti-diabetic drug, which controls blood sugar levels in the body and helps the pancreas to produce Insulin. The generic name of Glipizide is glipizide. The drug is used for treating type-2 Diabetes; it lowers the blood glucose by releasing the insulin from pancreas.

Glipizide 10mg

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What are Glipizide uses?

It is one of the oral diabetes medicines that is mainly used for controlling blood sugar levels by assisting your pancreas produce insulin. Glipizide for diabetes is mainly used along with diet as well as an exercise in order to improve the blood sugar control in adults suffering from type 2 diabetes mellitus.  

Do not use this medicine for treating type 1 diabetes. You can easily buy this medicine from our pharmacy at a reasonable cost.    

Glipizide generic drug is available in the brand name of Glucotrol.  

What is the dosage of Glipizide? 

You need to take this medicine by mouth at least 30 minutes before first meals or breakfast as prescribed by your doctor mainly once a day. There are some patients who take diabetes medication at a high dose so maybe the doctor tells to take this drug twice a day.  

The dosage of generic glipizide for diabetes which is available in different strengths like 5mg and 10mg is completely based on your medical conditions as well as response to your treatment.  

In order to reduce the risk of side effects, there might be chances that your doctor tells you to start this medication at a low dose and then gradually increase your dose with time. Make sure that you carefully follow your doctor’s instruction.  

There might be chances that your doctor tells to take this blood glucose medicine with food, take the medicine in the same manner as prescribed by your doctor.  

In case you are also taking another diabetes drug like chlorpropamide then it is important for you to follow doctor direction closely for stopping the old drug and starting blood glucose medicine.  

Colesevelam is known to decrease the absorption of this diabetes medicine. In case you are taking Colesevelam then take this medicine at least four hours before taking Colesevelam.   

If you want to get the most benefit from this diabetes medicine then you need to take it on a regular basis without skipping the dose. Ensure that you take this drug at the same time so that you remember taking it regularly.   

If your conditions worsen or do not improve then visit your doctor immediately. Do not take this medicine in smaller or larger amounts or for a longer time than recommended by your doctor. Do not crush, chew or break the Glipizide 5 mg or 10 mg tablet. Just swallow it whole.  

It is important for you to check your blood sugar frequently and also other blood tests at your doctor’s clinic. There are chances that the doctor might recommend this diabetes medication with other insulin medications.   

You might suffer from low blood sugar which is known as hypoglycaemia and feel shaky, hungry, irritable, anxious, dizzy as well as confused. In order to treat hypoglycaemia quickly, you need to eat or drink a fast-acting source of sugar such as hard candy, fruit juice, raisins, crackers or non-diet soda.   

Store the medicine at room temperature right away from heat, direct light as well as moisture. Thus, ensure that you take this drug as per your prescribing information.

What if you miss a dose? 

When you are getting ready to eat a meal then you need to take the dose as soon as possible. In case you skip the meal, then skip the missed dose and wait for your next mealtime. Don’t try to make two doses at the same time.  

What do you need to avoid while taking Glipizide? 

You need to avoid drinking alcohol as it can lower your blood sugar levels. You should also avoid driving as well as use any machinery that requires attention.  

Can you take Glipizide during pregnancy? 

If you are pregnant then use this diabetes medication exactly in the same manner as prescribed by your doctor. Remember that it is very important to keep your blood sugar in control during the pregnancy period due to which your doctor will change the dose of this medicine during each trimester.  

This medicine should not be taken during the last two weeks of pregnancy.  

Can a breastfeeding mother take Glipizide? 

When you are using this medication to lower blood sugar level then it might not be safe for you to breastfeed your baby. So before breastfeeding consult your doctor about all the risk involved.   

Precautions to be taken while using Glipizide 

You should strictly not use generic Glipizide tablets if you are allergic to it or suffering from diabetic ketoacidosis. It is always better to inform your doctor well in advance if you have ever suffered from:

  • Chronic diarrhoea
  • Liver or kidney disease
  • Blockage in your intestines
  • An enzyme deficiency which is known as glucose-6-phosphate dehydrogenase deficiency
  • Thyroid disease
  • Certain hormonal conditions
  • Electrolyte imbalance

This medicine is known to contain certain inactive ingredients that can cause allergic reactions or other problems so discuss about it in details with your doctor.  

During this medication, you might suffer from drowsiness, blurred vision or dizziness because of the extremely low or high blood sugar. So avoid drinking using machinery or involved in any activity which demands alertness & clear vision until and unless you are sure to perform it safely.  

What are the side effects of Glipizide? 

Some of the common side effects of this blood glucose medicine are: 

  • Skin rash, diarrhoea
  • Constipation, gas
  • Tremors, drowsiness
  • Dizziness
  • Redness or itching 

You need to consult your doctor immediately if you come across any signs of an allergic reaction this medicine like swelling of your lips, face, throat or tongue, hives and difficulty in breathing.  

Get the emergency medical help if you suffer from symptoms of low blood sugar:

  • Hunger, dizziness
  • Nausea, headache
  • Sweating, irritability
  • Fast heart rate as well as a feeling of anxious or shaky

Taking this drug and Metformin together can cause low blood sugar. But take both medicines together only when your doctor recommends.  

Intake of this medicine can make you more sensitive to the sun. So try to limit your exposure to the sun. Whenever you step out of the house, make sure that you use quality & effective sunscreen and wear protective clothing. 

Therefore, this is not the complete list of side effects, if you anything apart from this then contact your doctor immediately.  

How do Glipizide works? 

This medicine belongs to the class of sulfonylureas. This blood glucose medicine works by lowering the blood sugar by causing the pancreas to produce insulin as well as helping your body to use insulin efficiently.  

Glipizide Interactions 

Drug interaction can completely change how your medications work or can even increase your risk for severe side effects. So inform your doctor beforehand about all the products that you are taking such as prescription drugs, non-prescription drugs as well as herbal products. Do not start, stop or change the dose of any medicine without consulting to your doctor first.  

There are many drugs that can affect your blood sugar which makes it hard to control later. So it is important to consult your doctor before starting or stopping any medicine.  

There are total 430 drugs that are known to interact with this blood glucose medicine

19 major drug interactions

374 moderate drug interactions

37 minor drug interactions 

Here is the name of few drugs that interact with Glipizide tablets: Advil, Crestor, Glyburide, Invokana, Januvia, Lasix, Lyrica, Plavix, etc.  

Glipizide Warnings 

If you are suffering from diabetic ketoacidosis then you should not use this blood glucose medicine tablets strictly. 

We only ship medications which are approved by FDA, Also please consult your doctor to make a full decision on what medication to take.

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