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Home / Antibiotics / Ehionamide


The active ingredient of the drug Ehionamide. It is a very powerful antibiotic which

Ehionamide 250mg

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Ethionamide uses 

Ethionamide is usually given with other medications in order to treat tuberculosis. It is one of the antibiotics that work by stopping the growth of bacteria. This antibiotic is only capable of treating bacterial infections and does not work for viral infections. The Ethionamide brand name is Trecator and Trecator –SC. Therefore, using an antibiotic when not required can cause it to not work for future infections.  

Ethionamide dose 

You need to take this medicine with or without the food, mainly once daily or as directed by your doctor. In case this medicine causes stomach upset, nausea or vomiting, then you take it with meals. Consult with your doctor as he can help you in dividing the dose into smaller doses so that you can take it easily several times a day. Therefore, you need to follow your doctor’s instructions strictly.  

During the intake of this medicine, you need to have frequent blood tests in order to check your liver and thyroid function. You might also need frequent vision exams. If you are suffering diabetes, then kindly check your blood sugar carefully while taking Ethionamide.  

You need to use this medicine for the full prescribed length of time even if the symptoms improve before the infection is completely cleared. Skipping Ethionamide dosage for tuberculosis can increase the risk of further infection which is resistant to antibiotics. The doctor is also going you to direct for taking vitamin B6 in order to prevent certain side effects of this medicine. 

Therefore, store this medicine at room temperature right away from moisture as well as heat.  

The moment you remember, take the skipped dose but you need to skip the missed dose if it is time for your next scheduled dose. 

Ethionamide Side Effects 

Nausea, abdominal/stomach pain, increased saliva, diarrhea, vomiting, loss of appetite and sores in your mouth may occur. If all these effects persist or worsen then make sure that you immediately get the doctor's assistance.  

Remember one thing that the doctor has given you this medicine because he has judged that the benefit of Ethionamide is greater than the risk of side effects. There might be chances that many people using this medicine develop some serious side effects but the risk can be minimized by the frequent visit to doctor.  

Inform your doctor immediately, if any of these below stated unlikely but serious side effects occurs: 

  • Mental or mood changes
  • Slow heartbeat, joint pain or swelling
  • Yellowish eyes or skin and dark urine
  • Unusual hunger
  • Persistent nausea or vomiting 
  • Unusual tiredness or weakness
  • Unusual sweating as well as shakiness

Also tell your doctor if there are rare but serious vision changes such as color blindness, blurred, decreased or double vision as well as eye pain. You need to seek medical attention if you see any symptoms of a serious allergic reaction like severe dizziness, trouble breathing, rashes, itching as well as swelling in face, throat and tongue.  

Ethionamide Precautions 

Before taking this medicine, inform your doctor or pharmacist if you are allergic to it or have any other allergies. Since this medicine contains certain inactive ingredients so it can cause allergic reactions or other problems.  

Tell about your entire medical history, before the intake of this medicine if you are suffering from kidney disease, liver disease, eye problems as well as an underactive thyroid. While using this medication, you need to avoid alcoholic beverages because alcohol helps in increasing the risk of liver disease or mental and mood changes. 

Do not have any vaccinations or immunizations while using this medication because ethionamide does not allow live bacterial vaccines to work so well. Also, tell your doctor or dentist about all the products you use before having surgery.  

If you are suffering from diabetes, then this medicine can lower your blood sugar so don’t forget to check your blood sugar as directed and share the results with your doctor. There might be possibilities that you need to alter or adjust your diabetes medication, diet or exercise program. Inform your doctor if you have symptoms of low blood sugar like sudden sweating, fast heartbeat, hunger, blurred vision, tingling hands or feet, shaking as well as dizziness.  

This medicine is not recommended for pregnant ladies as it may harm the unborn baby. Therefore, also consult your doctor before breast-feeding.  

Ethionamide Interactions 

If you take the other drugs or herbal products at the same time then there are chances that the effects of some drugs change. This can help in increasing the risk for serious side effects or there might be possibilities that your medications do not work properly. Though these drug interactions are possible but it is not necessary that they occur always.  

In order to prevent or manage interactions, your doctor can change how you use your medications or by close monitoring. When you visit your doctor for the treatment, tell him about all the products that you are using currently such as prescription drugs, herbal products, non-prescription drugs. When you intake this medicine do not stop, start or change the dosage of any other medicines without the approval of your doctor. Keep a list of all the products you use so that the doctor can reduce the risk of all the serious medication problems.  

Total 103 drugs are known to interact with this medicine

9 major drug interactions

94 moderate drug interactions 

Ethionamide MOA (Mechanism of Action) 

Ethionamide is one of the prodrugs that are activated by the enzyme ethA which is a mono-oxygenase in Mycobacterium tuberculosis. This medicine works by stopping the growth of bacteria, while it only treats bacterial infections not viral infections such as common cold and flu.    

Ethionamide Warnings 

One should not take this medicine if he or she has severe liver disease. Also, avoid drinking alcohol when taking the tab ethionamide 250. The patient needs to adhere to the entire drug regimen for full duration of treatment.  

Therefore, keep this medicine out of reach of children and never share your medicine with another person even if he or she has the same symptom as yours. 

We only ship medications which are approved by FDA, Also please consult your doctor to make a full decision on what medication to take.

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