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Home / Antibiotics / Clavulanic


This drug is mainly a beta-lactamase inhibitor which is frequently combined with Amoxicillin or Ticarcillin in order to effectively fight against the antibiotic resistance by avoiding their degradation by beta-lactamase enzymes. When Clavulanic acid is combined along with other antibiotics it helps in preventing the development of drug-resistant strains of the bacteria and then further promotes their therapeutic antibacterial effect. Before you start the intake of this medicine make sure you consult your doctor once. This drug can be easily found at Pillsfind online pharmacy store with just a click of a mouse at a reasonable price.
Amoxicillin and Clavulanate Potassium

Clavulanic 1000mg

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What is clavulanic acid uses? 

This medicine is primarily a penicillin antibiotic which effectively fights against the bacteria present in your body. Clavulanate potassium is a beta-lactamase inhibitor which prevents certain bacteria from becoming resistant to amoxicillin.  

Amoxicillin and clavulanate potassium is a perfect combination of medicine which is utilized for treating several different infections that are majorly caused by bacteria like bronchitis, sinusitis, ear infections, urinary tract infections, pneumonia as well as infections of the skin.  

Amoxicillin clavulanic acid is known to work by stopping the growth of bacteria. Remember that this medicine is only going to treat bacterial infections and not work for viral infections like flu and the common cold.  

You should strictly not use any antibiotic when not needed because it will not work in future for treating infections effectively.  

You can use amoxicillin with certain other medications for treating stomach or intestinal ulcers that are caused by bacteria H.pylori as well as to prevent the ulcers from returning. But make sure that you first consult your doctor once.  

The generic drug is available in the brand name of augmentin and augmentin XR. 

What is amoxicillin clavulanic acid dosage? 

It is very important for you to take this drug exactly in the same manner as prescribed by your doctor. Strictly follow all the directions that are mentioned on your prescription label. You should never take this medicine in larger or smaller amounts or even for a longer time than recommended by your doctor.  

It is important for you to take amoxicillin clavulanic acid dosage every 12 hours that too at the start of the meal so that the problem of the upset stomach can be reduced.  

While you are taking the extended-release tablet, you should never crush or chew it. You need to directly swallow the whole pill or break the pill in half and then take both halves one at a time.  

In case you are finding trouble in swallowing a whole or half pill then inform your doctor because he might tell you to use another form of amoxicillin and clavulanate potassium.  

Before swallowing make sure that the chewable tablet is chewed first. If your doctor has prescribed you the liquid medicine then you should first shake it and measure the dose properly.  

It is very important for you to measure the liquid by using the dosing syringe which is provided with your medicine or make use of a special dose-measuring spoon or medicine cup. In case, you do not get the dose-measuring device ask your pharmacist to give one.  

You should never measure the liquid dose with a kitchen spoon as you might get the wrong dose.  

Remember that it is very important for you to take the medicine for the full prescribed length of time even if you see that your symptoms have completely improved before the infection is cleared completely.  

In case you skip any dose then there is a chance that your risk for further infection can be increased which is resistant to antibiotics. It is very important for you to understand this drug is not going to treat any kind of viral infections like common cold or flu.  

Augmentin amoxicillin medication can also cause uncommon results with few of your lab tests for glucose in the urine. So it is always better to inform your doctor well in advance who is treating you about this medicine.  

Since this medicine is available in different strengths so the 250mg and 500mg tablets of amoxicillin and clavulanic acid are known to contain the same amount of clavulanic acid. So it is always suggested not to substitute two 250mg tablets for one 500mg tablet.  

Remember one thing that 250mg regular tablet, as well as 250mg chewable tablet, contains different amounts of clavulanic acid so they should not be strictly substituted.  

Always store the tablets at room temperature where it is right away from direct light, heat as well as moisture. You also need to store the liquid medicine in the refrigerator. If you have any unused liquid augmentin XR then throw it away after 10 days.  

What happens if you miss a dose? 

As soon as you remember, make sure that you take the missed dose but if you see that it’s time for your next dose then skip the missed dose. In order to make up the missed dose, you should never take the extra medicine.   

What all you need to avoid while taking this medicine? 

It is important for you to avoid the intake of amoxicillin as well as clavulanate potassium together with or just after eating a high-fat meal as it will make it harder for your body to absorb the medication.  

You should also not take amoxicillin-clavulanate and alcohol together because it can cause serious side effects. Remember that antibiotic medicines can also cause diarrhoea which indicates the sign of new infection.  

So in case, you suffer from diarrhoea which is watery or bloody then immediately inform your doctor. Until and unless your doctor tells you, you should strictly not use anti-diarrhoea medicines.  

Can you take this medicine during pregnancy? 

It is still unknown whether this drug harms an unborn baby or not. If you are pregnant or planning to become pregnant then it is important for you to inform your doctor.  

The clavulanic acid drug is known to make birth control pills less effective. So it is better to ask your doctor about using non-hormonal birth control like a condom in order to successfully prevent pregnancy.  

Can a breastfeeding mother take this drug? 

Clavulanate potassium medicine is known to pass into breast milk due to which it affects the nursing baby. If you breast-feed your baby make sure that you inform your doctor beforehand.  

Precautions you need to take before starting this medicine 

Without consulting from a doctor, this medicine should strictly not be given to a child.  

Since Augmentin XR liquid, as well as a chewable tablet, is known to contain phenylalanine. So before you start the intake of this medicine make sure that you inform your doctor well in advance if you are suffering from phenylketonuria.  

If you suffer from clavulanic acid allergy then you should not strictly take this medicine. You should also immediately stop the intake of this drug and contact doctor for medical advice if you have: 

Serious kidney disease or even if you are on dialysis

Ever suffered from liver disease or jaundice while taking this medicine

You are allergic to any penicillin or cephalosporin antibiotic like Omnicef, Amoxil, Levaquin, Ceftin, Moxatag, Cefzil and many more 

In order to make sure that this medicine is safe for you to consume make sure that inform your doctor well in advance if you have ever suffered from:

  • Mononucleosis
  • Liver disease 
  • Kidney disease

Remember that augmentin amoxicillin can also cause live bacterial vaccines like typhoid vaccine not to work well. So when you are using the medicine it is always better to not have any kind of vaccinations or immunizations until and unless your doctor tells you to.  

If you need to have any kind of surgery then do inform your doctor about the usage of this medicine.  

What are the amoxicillin clavulanate side effects? 

Remember one thing that the doctor has prescribed you this medicine because he or she thinks that the benefit of this drug is more as compared to the risks of its side effects.  

While taking this medicine, if you come across any signs of an allergic reaction to this drug like swelling of your throat, face, lips or tongue, hives and difficulty in breathing then immediately contact your doctor medical help.  

There are very rare chances that this medicine might cause serious intestinal condition due to a type of resistant bacteria. You may suffer from this condition during the treatment or a week to months after the treatment has been stopped.    

In case you suffer from abdominal pain or stomach pain, blood or mucus in your stool, cramping or diarrhoea then you need to contact your doctor immediately. When suffering from all the above-stated symptoms then use should strictly not use anti-diarrhoea or opioid medications because there are chances that your symptoms might get worse.  

You need to get emergency medical help if you suffer from:

  • Loss of appetite jaundice as well as upper stomach pain
  • Serious stomach pain or diarrhoea which is bloody or watery
  • Little or no urination
  • Signs of serious skin reactionsuch as burning in your eyes, fever, skin pain followed by red or purple rash which spreads and causes blistering as well as peeling, sore throat and swelling in your face or tongue
  • Weakness, pale or yellow skin, confusion, dark coloured urine and fever
  • Easy bruising or bleeding

Some of the common side effects of this drug are:

  • Vaginal itching or discharge
  • Diarrhoea
  • Nausea

Therefore, this is not the complete list of side effects so if you experience anything apart from this then immediately contact your doctor.  

Amoxicillin / clavulanic acid interactions 

It is very important for you to understand that the effects of some drugs can be completely changed if you are also taking other drugs or herbal products at the same time. This will upsurge your risk for different serious side effects or might even make your medication not to work properly.  

This kind of drug interactions is possible but is not necessary that it occurs every time. So contact your doctor because he or she will help in preventing or managing the interactions by altering how you are using your medications currently or might keep you in close monitoring.  

In order to help your doctor to give the best care, you need to inform your doctor about all the products that you are using such as prescription drugs, non-prescription drugs as well as herbal products before your doctor starts the treatment.  

Without the approval of a doctor, you should not start, stop or change the dosage of any medicine. Methotrexate is one of the products that might interact with this drug.  

Since this medicine is known to lessen the effectiveness of birth control pills so make sure that you ask your doctor about this beforehand. When you visit your doctor make sure that you keep all the list of products that you are using.  

There are total 56 drugs that are known to interact with this clavulanic acid medication.

9 major drug interactions

39 moderate drug interactions

8 minor drug interactions 

Some of the drugs names that interacts with this medicine includes Advil, Flonase, Mucinex, Prednisone, Tylenol, vitamin D-3, Xanax, etc. 

Amoxicillin / clavulanic acid mechanism of action 

This medicine binds to penicillin-binding proteins within the bacterial cell wall as well as prevents bacterial cell wall synthesis. It acts through the inhibition of cell wall biosynthesis which helps in causing the death of the bacteria.  

Amoxicillin / clavulanic acid warnings 

This medicine should not be strictly used if you are suffering from kidney disease. In case, while taking this medicine you have ever suffered from a liver problem or jaundice then you should not take augmentin XR.  

If you are switching from one tablet form to another like chewable, extended-release or regular tablet then it is important for you to take only the new tablet form and strength which is given to you by your doctor.  

Amoxicillin clavulanic acid might not be as effective or can be harmful to you if you do not use the exact tablet form that is recommended by your doctor.  

We only ship medications which are approved by FDA, Also please consult your doctor to make a full decision on what medication to take.

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